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Larger exercise within the ventral striatum, the mind's reward heart, could buffer some people in opposition to the destructive psychological well being results of poor sleep. Credit score: Annchen R. Knodt, Duke College Poor sleep is each a threat issue, and a typical symptom, of despair. However not everybody who tosses and turns at night time turns into depressed. People whose brains are extra attuned to rewards could also be protected against the destructive psychological well being results of poor sleep, says a brand new research by Duke College neuroscientists. The researchers discovered that school college students with poor high quality sleep have been much less more likely to have signs of despair if in addition they had greater exerc...

By using virus genomics (genetic material), big data analysis and coding, the experts have devised a technique for predicting how patients are likely to respond to treatments that directly target mutated genes, without even coming into contact with the patient. The method has direct application on DNA-based drugs currently on the market, 32 drugs in clinical trials, as well as future therapies such as genome editing. The researchers achieved this by using a culture of human liver cancer cells that contain a non-infectious version of the Hep C virus, and drugs that treat Hep C by cutting and destroying its genome. As the Hep C virus is not good at copying its genome, it creates tens of billions of variants of itself in these cells: this is similar to the genetic variation which could be found in the wider population. The experts then tested the drugs on the cultures, and examined the impact of each of these drugs on each individual variant of Hep C, to determine which drugs work o...